Pyrimidines And Derivatives
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Filtered Search Results
Medchemexpress LLC PEG8-Tos | 886469-23-4 | 250 MG
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PEG8-Tos is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This chemical reagent is for research use only and not intended for human use.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Molecular weight: 524.62
- Chemical formula: C23H40O11S
- Appearance: Liquid
- Color: Colorless to light yellow
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Medchemexpress LLC (±)-Silybin (Silibinin) | 36804-17-8 | 99.4% | 482.44 | 250 MG
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(±)-Silybin is the racemate of Silybin and is known for inducing apoptosis. It exhibits a range of biological activities including hepatoprotective, antioxidant, anti-inflammatory, and anti-cancer effects. This compound has a chemical formula of C25H22O10, appears as a white to off-white solid, and is classified under Flavonoids and Flavanonols.
- Induces apoptosis.
- Exhibits hepatoprotective, antioxidant, anti-inflammatory, and anti-cancer activities.
- Appears as a white to off-white solid.
- Classified as a flavonoid and flavanonol.
- Derived from Leguminosae and Compositae plant families.
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Medchemexpress LLC Methyl DL-pyroglutamate | 54571-66-3 | 97.37% | 143.14 | 25 G
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Methyl DL-pyroglutamate is a biochemical reagent intended for research use only. It is not sold to patients.
- Appearance: Solid below 21°C, liquid above 23°C
- Color: Colorless to light yellow
- Shipping: Room temperature in continental US
- Storage: Store at room temperature for 3 years; in solvent: -80°C for 2 years, -20°C for 1 year
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Medchemexpress LLC 3-Cyanoumbelliferone | 19088-73-4 | ≥98.0% | 250 MG
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3-Cyanoumbelliferone is a coumarin derivative that acts as a molecular probe and fluorescent dye. It is also a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a Ki of 2.9 μM.
- Acts as a molecular probe and fluorescent dye.
- Macrophage migration inhibitory factor (MIF) tautomerase inhibitor.
- Has a molecular weight of 187.15.
- Chemical formula is C10H5NO3.
- Appears as a solid with a yellow to orange color.
- Has a solubility of 6.67 mg/mL in DMSO (35.64 mM), requiring ultrasonic, warming, and heating to 60 °C.
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Medchemexpress LLC Ethyl 3-azidopropanoate | 40139-55-7 | MFCD24452394 | >95.0% | 143.14 g·mol⁻1 | C5H9N3O2 | 25 MG
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Ethyl 3-azidopropanoate is an ethyl ester bearing a terminal azide group used as a building block in organic synthesis and click-chemistry applications. The azide functionality readily undergoes cycloaddition with alkynes to form stable triazole linkages, enabling modular assembly and bioconjugation.
- Azide-functional ethyl ester for click chemistry.
- Reacts in copper-catalyzed and strain-promoted cycloadditions to yield triazoles.
- High purity (≥95.0%) suitable for synthetic applications.
- Liquid, colorless to light yellow, facilitating handling and dosing.
- Recommended storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months).
- Supplied as a 25 mg aliquot for small-scale synthesis and screening.
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Medchemexpress LLC m-PEG-triethoxysilane (MW 5000) | 547701-35-9 | 98.0% | C15H34N2O6Si | 250 MG
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m-PEG-triethoxysilane (MW 5000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules are designed to selectively degrade target proteins by leveraging the intracellular ubiquitin-proteasome system. It has an average molecular weight of 5000 and appears as a white to off-white solid.
- Functions as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Appears as a white to off-white solid
- Stable for up to 3 years as powder at -20°C
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Chemscene ChemScene | 2-Methylpyrimidine-5-carboxylic acid | 5G | CS-W016511 | 0.98 | 5194-32-1| MFCD08235210 | 138.13
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ChemScene | 2-Methylpyrimidine-5-carboxylic acid | 5G | CS-W016511 | 0.98 | 5194-32-1| MFCD08235210 | 138.13
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Matrix Scientific 2-METHYL-5-PYRIMIDINECARBOXY-1
2-methyl-5-pyrimidinecarboxylic Acid Mf C6h6n2o2 Mw 138.13 Cas 5194-32-1 Mdl MFCD08235210
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Medchemexpress LLC Ethyl 1-(2-bromoacetyl)cyclopropanecarboxylate | 129306-05-4 | 97.1% | 235.08 | 1 G
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Ethyl 1-(2-bromoacetyl)cyclopropanecarboxylate is a drug intermediate for the synthesis of various active compounds.
- Identified for laboratory chemical use
- Suitable for the manufacture of substances
- For research use only
- Store pure form at -20°C for 3 years, or 4°C for 2 years
- Store in solvent at -80°C for 6 months, or -20°C for 1 month
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Medchemexpress LLC 4-pyrimidinecarboxylic acid, methyl ester | 2450-08-0 | MFCD00234184 | 99.0% | 138.12 | C6H6N2O2 | 500 MG
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Methyl pyrimidine-4-carboxylate (4-pyrimidinecarboxylic acid, methyl ester) is a synthetic intermediate used in pharmaceutical and organic synthesis. It is supplied as a high-purity powder for research use.
- High HPLC purity: 98.96% (batch COA).
- Molecular formula C6H6N2O2, molecular weight 138.12 g/mol.
- Typical amount: 500 mg per package.
- Storage stability: powder - 3 years at -20°C, 2 years at 4°C; in solvent - 6 months at -80°C, 1 month at -20°C.
- Intended for research use as a synthetic building block in medicinal chemistry and organic synthesis.
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eMolecules 2410796-79-9 | Sovilnesib | Ambeed564.650 | C26H34F2N6O4S | 98.000 | Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC3)CC2)nc(n1)N1CCC(F)(F)CC1 | 10mg | 837384736
Sovilnesib | Ambeed | 2410796-79-9564.650 | C26H34F2N6O4S | 98.000 | Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC3)CC2)nc(n1)N1CCC(F)(F)CC1 | 10mg | 837384736
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eMolecules 2004724-16-5 | Mal-Dap(Boc)-OH??DCHA | Ambeed | MFCD27952860 | 465.591 | C24H39N3O6 | 95.000 | C1CCC(CC1)NC1CCCCC1.CC(C)(C)OC(=O)NC[C@H](N1C(=O)C=CC1=O)C(O)=O | 250mg | 784396575
Mal-Dap(Boc)-OH??DCHA | Ambeed | 2004724-16-5 | MFCD27952860 | 465.591 | C24H39N3O6 | 95.000 | C1CCC(CC1)NC1CCCCC1.CC(C)(C)OC(=O)NC[C@H](N1C(=O)C=CC1=O)C(O)=O | 250mg | 784396575
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Medchemexpress LLC Methyl arachidate (methyl icosanoate) | 1120-28-1 | MFCD00009014 | 326.56 | 5 G
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Methyl arachidate (Methyl icosanoate) is a component of lipid mixtures. It can be isolated from flowering plants, inhibits LTA4H, and shows no antifeedant activity against *Leptinotarsa decemlineata*.
- Component of lipid mixtures
- Can be isolated from flowering plants
- Inhibits LTA4H
- Shows no antifeedant activity against *Leptinotarsa decemlineata*
- Solid, white to off-white appearance
- Molecular formula C21H42O2
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Medchemexpress LLC Dibenzo[b,k]hexaoxacyclooctadecin, eicosahydro- | 16069-36-6 | 97.0% | 372.50 | 250 MG
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Dicyclohexano-18-crown-6-ether selectively extracts lysine-rich cytochrome c proteins from other cationic proteins under weakly acidic and neutral conditions, demonstrating specificity in ligand-protein interactions.
- Selectively extracts lysine-rich cytochrome c proteins from other cationic proteins.
- Demonstrates specificity in ligand-protein interactions.
- Shows antiproliferative activity against various cell lines (HeLa, MCF7, MIA PaCa-2, NCI-H460, SW-620).
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Medchemexpress LLC Ethyl 3-hydroxybutyrate | 5405-41-4 | 99.99% | 132.16 | 100 G
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Ethyl 3-hydroxybutyrate is a fragrance found in wine and the insect *Tribolium castaneum*. It has been studied for its therapeutic potential in alleviating skeletal muscle wasting in cancer cachexia by increasing 3-HB levels and promoting the TCA cycle.
- Increases 3-HB levels in serum
- Promotes TCA cycle and protein synthesis
- Improves metabolic homeostasis
- Reduces inflammation and enhances antioxidant capacity
- Alleviates cancer cachexia-associated skeletal muscle atrophy
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